Article
The p75 neurotrophin receptor protects primary auditory neurons against acoustic trauma in mice.
Hearing research - 1 Sept 2010
Tan Justin, Clarke Maria, Barrett G, Millard R
Abstract excerpt
In the adult rodent inner ear, p75NTR is weakly expressed in primary auditory neurons (PANs) and cochlear Schwann cells. When the organ of Corti is damaged during trauma, its expression dramatically increases. It is unclear what role p75NTR plays under these conditions. Characterisation of p75NTR mutant mice reveals that altering genetic backgrounds can differentially affect the survival of PANs in mutant mice....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.