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Article

Genomic and geographic distribution of SNP-defined runs of homozygosity in Europeans.

Human molecular genetics - 1 Aug 2010

Nothnagel Michael, Lu Timothy Tehua, Kayser Manfred, Krawczak Michael

Abstract excerpt

The availability of high-density panels of genetic polymorphisms has led to the discovery of extended regions of apparent autozygosity in the human genome. At the genotype level, these regions present as sizeable stretches, or 'runs', of homozygosity (ROH). Here, we investigated both the genomic and the geographic distribution of ROHs in a large European sample of individuals originating from 23 subpopulations....

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PMID: 20462934
DOI: 10.1093/hmg/ddq198

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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