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Article

Association of the human leucocyte antigen region with susceptibility to Parkinson's disease.

Journal of neurology, neurosurgery, and psychiatry - 1 Aug 2010

Saiki Misuzu, Baker Amie, Williams-Gray Caroline H, Foltynie Thomas, Goodman Reyna S, Taylor Craig J, Compston D Alastair S, Barker Roger A, Sawcer Stephen J, Goris An

Abstract excerpt

OBJECTIVE: The core pathology of Parkinson's disease (PD) is a loss of the dopaminergic neurons in the nigro-striatal pathway, but this is only part of a more widespread pathological process, the nature of which is unknown. Recent data suggest a possible role for inflammation in this disease process. The Human Leucocyte Antigen (HLA) region is one of the most important genetic susceptibility factors in many...

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Share to Disease Susceptibility
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20462916
DOI: 10.1136/jnnp.2008.162883

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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