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Article

A single nucleotide polymorphism in the E-cadherin gene promoter -160 C/A is associated with risk of nasopharyngeal cancer.

Clinica chimica acta; international journal of clinical chemistry - 6 Sept 2010

Ben Nasr Hela, Hamrita Bechr, Batbout Mariem, Gabbouj Sallouha, Bouaouina Noureddine, Chouchane Lotfi, Chahed Karim

Abstract excerpt

BACKGROUND: E-cadherin is a cell structural protein that has a pivotal role in cell-cell adhesion and epithelial development. Up to now, loss of activity of E-cadherin is believed to contribute to progression in several neoplastic diseases of epidermoid origin including nasopharyngeal carcinomas (NPC) by increasing invasion and proliferation. Besides, functional genetic variations in the promoter region of the...

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PMID: 20462505
DOI: 10.1016/j.cca.2010.05.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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