Article
E-cadherin-160 C/A promoter polymorphism and risk of pancreatic carcinoma in Chinese population.
Cancer genetics and cytogenetics - 1 Feb 2010
Fei Yang, Hu Jian, Liu Shengli, Liu Xushun, Wang Feng, Gong Jieming
Abstract excerpt
Recent studies have implicated E-cadherin-160C/A single-nucleotide polymorphism (SNP) in susceptibility to and early onset of some cancers. We investigated the role of E-cadherin-160 C/A SNP in Chinese pancreatic carcinoma patients without dominant family history by genotyping 254 patients and 101 controls. The risk of cancer for CC genotype individuals was less than half that of AA individuals [odds ratio (OR) =...
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