Functional vascular endothelial growth factor -2578 C/A polymorphism in relation to nasopharyngeal carcinoma risk and tumor progression.

doi:10.1016/j.cca.2008.05.022

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Article

Functional vascular endothelial growth factor -2578 C/A polymorphism in relation to nasopharyngeal carcinoma risk and tumor progression.

Clinica chimica acta; international journal of clinical chemistry - 1 Sept 2008

Nasr Hela Ben, Chahed Karim, Bouaouina Noureddine, Chouchane Lotfi

Abstract excerpt

BACKGROUND: Vascular endothelial growth factor (VEGF) is a mitogen for endothelial cells and a potent regulator of angiogenesis and inflammatory processes in nasopharyngeal carcinomas. In the current report, we designed a case-controlled study to evaluate whether a genetically predetermined variation in the VEGF expression may affect susceptibility and prognosis. METHODS: A PCR and restriction fragment length...

Topics

Adult
Alleles
Case-Control Studies
Disease Progression
Female
Genetic Variation
Genotype
Humans
Male
Nasopharyngeal Neoplasms
Neoplasm Staging
Polymerase Chain Reaction
Polymorphism, Genetic

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Restriction Fragment Length

Polymorphism, Single Nucleotide

Prognosis

Promoter Regions, Genetic

Risk Factors

Source

Open in PubMed

Identifiers

PMID: 18588866
DOI: 10.1016/j.cca.2008.05.022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.