-2548G>A LEP Polymorphism Is Positively Associated with Increased Leptin and Glucose Levels in Obese Saudi Patients Irrespective of Blood Pressure Status

doi:10.3390/medicina58030346

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-2548G>A LEP Polymorphism Is Positively Associated with Increased Leptin and Glucose Levels in Obese Saudi Patients Irrespective of Blood Pressure Status

Medicina (Kaunas, Lithuania) - 24 Feb 2022

Sabi Essa M, Bin Dahman Lotfi S, Mohammed Abdul Khader, Sumaily Khalid M, Al-Daghri Nasser M

Abstract excerpt

Background and Objectives: In this study, we aimed to investigate the link between common -2548G>A (rs7799039) promoter variant of the human leptin gene (LEP) with leptin and serum glucose leptin levels in obese Saudi patients. Materials and Methods: A total of 206 Saudi adults (80 obese normotensive nondiabetics, 76 obese hypertensive with Type 2 Diabetes and 50 normotensive nondiabetic controls) were genotyped...

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PMID: 35334523
DOI: 10.3390/medicina58030346
PMCID: PMC8955012

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