Article
Replication analysis confirms the association of ARID5B with childhood B-cell acute lymphoblastic leukemia.
Haematologica - 1 Sept 2010
Healy Jasmine, Richer Chantal, Bourgey Mathieu, Kritikou Ekaterini A, Sinnett Daniel
Abstract excerpt
Although childhood acute lymphoblastic leukemia is the most common pediatric cancer, its etiology remains poorly understood. In an attempt to replicate the findings of 2 recent genome-wide association studies in a French-Canadian cohort, we confirmed the association of 5 SNPs [rs7073837 (P=4.2 x 10(-4)), rs10994982 (P=3.8 x 10(-4)), rs10740055 (P=1.6 x 10(-5)), rs10821936 (P=1.7 x 10(-7)) and rs7089424 (P=3.6 x...