Article
Genetic studies of African populations: an overview on disease susceptibility and response to vaccines and therapeutics.
Human genetics - 1 Jul 2008
Sirugo Giorgio, Hennig Branwen J, Adeyemo Adebowale A, Matimba Alice, Newport Melanie J, Ibrahim Muntaser E, Ryckman Kelli K, Tacconelli Alessandra, Mariani-Costantini Renato, Novelli Giuseppe, Soodyall Himla, Rotimi Charles N, Ramesar Raj S, Tishkoff Sarah A, Williams Scott M
Abstract excerpt
Africa is the ultimate source of modern humans and as such harbors more genetic variation than any other continent. For this reason, studies of the patterns of genetic variation in African populations are crucial to understanding how genes affect phenotypic variation, including disease predisposition. In addition, the patterns of extant genetic variation in Africa are important for understanding how genetic...
Topics
- Africa
- Communicable Diseases
- Genetic Predisposition to Disease
- Genetic Testing
- Genome, Human
- Humans
- Immunotherapy, Active
- Metabolic Diseases
- Neoplasms