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Article

The Complex World of Regulation of Pituitary Growth Hormone Secretion: The Role of Ghrelin, Klotho, and Nesfatins in It.

Frontiers in endocrinology - 1 Jan 2021

Devesa Jesús

Abstract excerpt

The classic concept of how pituitary GH is regulated by somatostatin and GHRH has changed in recent years, following the discovery of peripheral hormones involved in the regulation of energy homeostasis and mineral homeostasis. These hormones are ghrelin, nesfatins, and klotho. Ghrelin is an orexigenic hormone, released primarily by the gastric mucosa, although it is widely expressed in many different tissues,...

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Identifiers

PMID: 33776931
DOI: 10.3389/fendo.2021.636403
PMCID: PMC7991839

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