Article
Living on the edge: stress and activation of stress responses promote lifespan extension.
Aging - 1 Apr 2010
Zuin Alice, Castellano-Esteve David, Ayté José, Hidalgo Elena
Abstract excerpt
Oxidative stress constitutes the basis of physio-pathological situations such as neurodegenerative diseases and aging. However, sublethal exposure to toxic molecules such as reactive oxygen species can induce cellular responses that result in stress fitness. Studies in Schizosaccharomyces pombe have recently showed that the Sty1 MAP kinase, known to be activated by hydrogen peroxide and other cellular stressors,...
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