Article
A genome-wide screen for depression in two independent Dutch populations.
Biological psychiatry - 15 Jul 2010
Schol-Gelok Suzanne, Janssens A Cecile J W, Tiemeier Henning, Liu Fan, Lopez-Leon Sandra, Zorkoltseva Irina V, Axenovich Tatiana I, van Swieten John C, Uitterlinden André G, Hofman Albert, Aulchenko Yurii S, Oostra Ben A, van Duijn Cornelia M
Abstract excerpt
BACKGROUND: Depression has a strong genetic component but candidate gene studies conducted to date have not shown consistent associations. METHODS: We conducted a genome-wide parametric and nonparametric linkage analysis in a large-scale family-based study including 115 individuals with depression who were identified based on the Hospital Anxiety Depression Scale, Center for Epidemiologic Studies Depression...
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