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Article

Genetic variation associated with preterm birth in African-American women.

American journal of obstetrics and gynecology - 1 Aug 2016

Frey Heather A, Stout Molly J, Pearson Laurel N, Tuuli Methodius G, Cahill Alison G, Strauss Jerome F, Gomez Luis M, Parry Samuel, Allsworth Jenifer E, Macones George A

Abstract excerpt

BACKGROUND: Preterm birth is considered a multifactorial condition; however, emerging evidence suggests that genetic variation among individuals may have an important role. Prior studies have suggested that single-nucleotide polymorphisms associated with genes related to the immune system, and particularly the maternal inflammatory response, may be associated with an increased risk of preterm delivery. OBJECTIVE:...

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Identifiers

PMID: 26979631
DOI: 10.1016/j.ajog.2016.03.008
PMCID: PMC4967390

Genes

PRKCA
MMP2
FLT1
LIFR
MMP1
TIMP2

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