Article
Racial disparity in pathophysiologic pathways of preterm birth based on genetic variants.
Reproductive biology and endocrinology : RB&E - 15 Jun 2009
Menon Ramkumar, Pearce Brad, Velez Digna R, Merialdi Mario, Williams Scott M, Fortunato Stephen J, Thorsen Poul
Abstract excerpt
OBJECTIVE: To study pathophysiologic pathways in spontaneous preterm birth and possibly the racial disparity associating with maternal and fetal genetic variations, using bioinformatics tools. METHODS: A large scale candidate gene association study was performed on 1442 SNPs in 130 genes in a case (preterm birth < 36 weeks) control study (term birth > 37 weeks). Both maternal and fetal DNA from Caucasians (172...
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