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Article

Roles of cysteines Cys115 and Cys201 in the assembly and thermostability of grouper betanodavirus particles.

Virus genes - 1 Aug 2010

Wang Chun-Hsiung, Hsu Chi-Hsin, Wu Yi-Min, Luo Yu-Chun, Tu Mei-Hui, Chang Wei-hau, Cheng R Holland, Lin Chan-Shing

Abstract excerpt

The virus-like particle (VLP) assembled from capsid subunits of the dragon grouper nervous necrosis virus (DGNNV) is very similar to its native T = 3 virion. In order to investigate the effects of four cysteine residues in the capsid polypeptide on the assembly/dissociation pathways of DGNNV virions, we recombinantly cloned mutant VLPs by mutating each cysteine to destroy the specific disulfide linkage as...

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Identifiers

PMID: 20446029
DOI: 10.1007/s11262-010-0488-1
PMCID: PMC2886913

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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