Article
Involvement of the terminus of grouper betanodavirus capsid protein in virus-like particle assembly.
Archives of virology - 1 Feb 2003
Lu M W, Lin C S
Abstract excerpt
Dragon grouper, Epinephelus lanceolatus, nervous necrosis virus (DGNNV) consists of 180 copies of capsid protein that encapsulates a bipartite genome of single-stranded (+)RNAs. Expressing the open reading frame (ORF) of RNA2 in Escherichia coli forms virus-like particles (VLPs) that resembles native virus. Deleting N- and C-termini revealed different impacts on VLP formation. Deletion of 35 or 52 residues at the...
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