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Article

Virus maturation targets the protein capsid to concerted disassembly and unfolding.

The Journal of biological chemistry - 26 May 2000

Oliveira A C, Gomes A M, Almeida F C, Mohana-Borges R, Valente A P, Reddy V S, Johnson J E, Silva J L

Abstract excerpt

Many animal viruses undergo post-assembly proteolytic cleavage that is required for infectivity. The role of maturation cleavage on Flock House virus was evaluated by comparing wild type (wt) and cleavage-defective mutant (D75N) Flock House virus virus-like particles. A concerted dissociation and unfolding of the mature wt particle was observed under treatment by urea, whereas the cleavage-defective mutant...

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Share to Baculoviridae
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10748191
DOI: 10.1074/jbc.M910145199

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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