Article
Human papillomavirus 16 minor capsid protein L2 helps capsomeres assemble independently of intercapsomeric disulfide bonding.
Virus genes - 1 Dec 2005
Ishii Yoshiyuki, Ozaki Saori, Tanaka Keiko, Kanda Tadahito
Abstract excerpt
The human papillomavirus (HPV) capsomeres (pentamers of major capsid protein L1), which constitute along with L2 the virion capsid, can assemble themselves alone into the L1-capsid particles in vivo and in vitro, depending on intercapsomeric disulfide bonds. To study a possible role of L2 in capsid assembly, we examined the interaction between HPV16 L2 and capsomeres under the conditions that inhibit the...
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