Methylation of ribosomal protein L42 regulates ribosomal function and stress-adapted cell growth.

doi:10.1074/jbc.M110.132274

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Article

Methylation of ribosomal protein L42 regulates ribosomal function and stress-adapted cell growth.

The Journal of biological chemistry - 16 Jul 2010

Shirai Atsuko, Sadaie Mahito, Shinmyozu Kaori, Nakayama Jun-ichi

Abstract excerpt

Lysine methylation is one of the most common protein modifications. Although lysine methylation of histones has been extensively studied and linked to gene regulation, that of non-histone proteins remains incompletely understood. Here, we show a novel regulatory role of ribosomal protein methylation. Using an in vitro methyltransferase assay, we found that Schizosaccharomyces pombe Set13, a SET domain protein...

Topics

Adaptation, Physiological
Amino Acid Sequence
Cell Line
Cell Nucleus
Cell Proliferation
Chromatography, Liquid
Cold Temperature
Conserved Sequence
Cycloheximide
Humans
Lysine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mass Spectrometry

Methylation

Methyltransferases

Molecular Sequence Data

Mutation

Protein Transport

Recombinant Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 20444689
DOI: 10.1074/jbc.M110.132274
PMCID: PMC2903366

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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-20444689-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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