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Article

A novel SET domain methyltransferase modifies ribosomal protein Rpl23ab in yeast.

The Journal of biological chemistry - 14 Oct 2005

Porras-Yakushi Tanya R, Whitelegge Julian P, Miranda Tina Branscombe, Clarke Steven

Abstract excerpt

In vivo studies have shown that the ribosomal large subunit protein L23a (Rpl23ab) in Saccharomyces cerevisiae is methylated at lysine residues. However, the gene encoding the methyltransferase responsible for the modification has not been identified. We show here that the yeast YPL208w gene product, a member of the SET domain family of methyltransferases, catalyzes the reaction, and we have now designated it...

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Source

Identifiers

PMID: 16096273
DOI: 10.1074/jbc.M507672200

Genes

SET
SDS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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A novel SET domain methyltransferase modifies ribosomal protein Rpl23ab in yeast.PMID 16096273Read ↗

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