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Alterations in Hematopoietic Microenvironment in Patients with Aplastic Anemia

1 Feb 2009

Abstract excerpt

Mechanisms of hematopoietic failure in patients with aplastic anemia (AA) are obscure. We investigate alterations in the hematopoietic microenvironment in AA patients. We present the results of studying mesenchymal stromal cells (MSC), fibroblastic colony-forming units (CFU-F), and adherent cell layers (ACL) of long-term bone marrow cultures (LTBMC) from bone marrow (BM) samples of AA patients. MSC of AA patients...

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PMID: 20443870
DOI: 10.1111/j.1752-8062.2008.00074.x

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