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Article

Bone marrow adipocytes support hematopoietic stem cell survival.

Journal of cellular physiology - 1 Feb 2018

Mattiucci Domenico, Maurizi Giulia, Izzi Valerio, Cenci Lorenzo, Ciarlantini Marco, Mancini Stefania, Mensà Emanuela, Pascarella Raffaele, Vivarelli Marco, Olivieri Attilio, Leoni Pietro, Poloni Antonella

Abstract excerpt

In bone marrow (BM), hematopoietic elements are mingled with adipocytes (BM-A), which are the most abundant stromal component in the niche. BM-A progressively increase with aging, eventually occupying up to 50% of BM cavities. In this work, the role played by BM-A was explored by studying primary human BM-A isolated from hip surgery patients at the molecular level, through microarray analysis, and at the...

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Share to Adipocytes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colony-Stimulating Factors

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Share to Leukemia Inhibitory Factor

Share to Stem Cell Niche

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Source

Identifiers

PMID: 28574591
DOI: 10.1002/jcp.26037

Genes

MSC
CSF3
CXCL12
LIF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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