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Gene expression profiling in CD34 cells to identify differences between aplastic anemia patients and healthy volunteers

22 Sept 2003

Abstract excerpt

An immune pathophysiology for acquired aplastic anemia (AA) has been inferred from the responsiveness of the patients to immunosuppressive therapies and experimental laboratory data. To address the transcriptome of hematopoietic cells in AA, we undertook GeneChip analysis of the extremely limited numbers of progenitor and stem cells in the marrow of patients with this disease. We pooled total RNA from highly...

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PMID: 14504100
DOI: 10.1182/blood-2003-02-0490

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