Article
Differential gene expression profile associated with the abnormality of bone marrow mesenchymal stem cells in aplastic anemia.
PloS one - 1 Jan 2012
Li Jianping, Yang Shaoguang, Lu Shihong, Zhao Hui, Feng Jianming, Li Wenqian, Ma Fengxia, Ren Qian, Liu Bin, Zhang Lei, Zheng Yizhou, Han Zhong Chao
Abstract excerpt
Aplastic anemia (AA) is generally considered as an immune-mediated bone marrow failure syndrome with defective hematopoietic stem cells (HSCs) and marrow microenvironment. Previous studies have demonstrated the defective HSCs and aberrant T cellular-immunity in AA using a microarray approach. However, little is known about the overall specialty of bone marrow mesenchymal stem cells (BM-MSCs). In the present...
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