Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA-340-mediated degradation of microphthalmia-associated transcription factor mRNA is inhibited by the coding region determinant-binding protein.

The Journal of biological chemistry - 2 Jul 2010

Goswami Srikanta, Tarapore Rohinton S, Teslaa Jessica J, Grinblat Yevgenya, Setaluri Vijayasaradhi, Spiegelman Vladimir S

Abstract excerpt

Alternative cleavage and polyadenylation generate multiple transcript variants of mRNA isoforms with different length of 3'-untranslated region (UTR). Alternative cleavage and polyadenylation enable differential post-transcriptional regulation of transcripts via the availability of different cis-acting elements in 3'-UTRs. Microphthalmia-associated transcription factor (MITF) is a master regulator of melanocyte...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Gene Amplification

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Reporter

Share to Melanocytes

Share to Melanoma

Share to Microphthalmia-Associated Transcription Factor

Share to MicroRNAs

Share to RNA, Neoplasm

Source

Open in PubMed Open full text

Identifiers

PMID: 20439467
DOI: 10.1074/jbc.M110.109298
PMCID: PMC2898355

Genes

MITF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA-340-mediated degradation of microphthalmia-associated transcription factor mRNA is inhibited by the coding region determinant-binding protein.PMID 20439467Read ↗

MicroRNA-137 targets microphthalmia-associated transcription factor in melanoma cell lines.Semantic proximity Read ↗

MicroRNA-218 inhibits melanogenesis by directly suppressing microphthalmia-associated transcription factor expressionSemantic proximity Read ↗

MITF: master regulator of melanocyte development and melanoma oncogene.Semantic proximity Read ↗

Microphthalmia-Associated Transcription Factor: A Differentiation Marker in Uveal MelanomaSemantic proximity Read ↗

Microphthalmia-associated transcription factor (MITF): multiplicity in structure, function, and regulation.Semantic proximity Read ↗

Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells.Semantic proximity Read ↗

Structural organization of the human microphthalmia-associated transcription factor gene containing four alternative promoters.Semantic proximity Read ↗

In vivo role of alternative splicing and serine phosphorylation of the microphthalmia-associated transcription factor.Semantic proximity Read ↗

Mitf-D, a newly identified isoform, expressed in the retinal pigment epithelium and monocyte-lineage cells affected by Mitf mutations.Semantic proximity Read ↗

Downregulation of CFIm25 amplifies dermal fibrosis through alternative polyadenylationSemantic proximity Read ↗

Effect of a natural mutation in the 5' untranslated region on the translational control of p53 mRNA.Semantic proximity Read ↗

Identification of a distal enhancer for the melanocyte-specific promoter of the MITF gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.