Article
Mitf-D, a newly identified isoform, expressed in the retinal pigment epithelium and monocyte-lineage cells affected by Mitf mutations.
Biochimica et biophysica acta - 20 Feb 2002
Takeda Kazuhisa, Yasumoto Ken ichi, Kawaguchi Naoko, Udono Tetsuo, Watanabe Ken ichi, Saito Hideo, Takahashi Kazuhiro, Noda Masaki, Shibahara Shigeki
Abstract excerpt
Microphthalmia-associated transcription factor (Mitf) regulates the differentiation of melanocytes, optic cup-derived retinal pigment epithelium (RPE), and some types of bone marrow-derived cells. Mitf consists of at least five isoforms with different N-termini, each of which is encoded by a separate exon 1. Here we identified a novel isoform, termed mouse Mitf-D/human MITF-D, that is expressed in RPE,...
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