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Article

Influence of ABCB1 genetic polymorphisms on the pharmacokinetics of levosulpiride in healthy subjects.

Neuroscience - 11 Aug 2010

Cho H Y, Yoo H D, Lee Y B

Abstract excerpt

The purposes of this study were to clarify the involvement of P-glycoprotein in the absorption of levosulpiride in knockout mice that lack the Abcb1a/ 1b gene, and to evaluate the relationship between genetic polymorphisms in ABCB1 (exon 12, 21 and 26) and levosulpiride disposition in healthy subjects. The plasma and brain samples were obtained after oral administration (10 microg/g) of levosulpiride to...

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Identifiers

PMID: 20438811
DOI: 10.1016/j.neuroscience.2010.04.065

Genes

ABCB1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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