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Article

Allele-specific expression of APC in adenomatous polyposis families.

Gastroenterology - 1 Aug 2010

Castellsagué Ester, González Sara, Guinó Elisabet, Stevens Kristen N, Borràs Ester, Raymond Victoria M, Lázaro Conxi, Blanco Ignacio, Gruber Stephen B, Capellá Gabriel

Abstract excerpt

BACKGROUND & AIMS: Germline mutations in the APC gene cause of most cases of familial adenomatous polyposis (FAP) and a lesser proportion of attenuated FAP (AFAP). Systematic analysis of APC at the RNA level could provide insight into the pathogenicity of identified mutations and the molecular basis of FAP/AFAP in families without identifiable mutations. Here, we analyzed the prevalence of imbalances in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to DNA Glycosylases

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Source

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Identifiers

PMID: 20434453
DOI: 10.1053/j.gastro.2010.04.047
PMCID: PMC2910837

Genes

APC
FAP
MUTYH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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