Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Correlation between mutations and mRNA expression of APC and MUTYH genes: new insight into hereditary colorectal polyposis predisposition.

Journal of experimental & clinical cancer research : CR - 28 Oct 2015

Aceto Gitana Maria, Fantini Fabiana, De Iure Sabrina, Di Nicola Marta, Palka Giandomenico, Valanzano Rosa, Di Gregorio Patrizia, Stigliano Vittoria, Genuardi Maurizio, Battista Pasquale, Cama Alessandro, Curia Maria Cristina

Abstract excerpt

BACKGROUND: Transcript dosage imbalance may influence the transcriptome. To gain insight into the role of altered gene expression in hereditary colorectal polyposis predisposition, in the present study we analyzed absolute and allele-specific expression (ASE) of adenomatous polyposis coli (APC) and mutY Homolog (MUTYH) genes. METHODS: We analyzed DNA and RNA extracted from peripheral blood mononuclear cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenomatous Polyposis Coli
Share to Adenomatous Polyposis Coli Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to DNA Glycosylases

Share to DNA Mutational Analysis

Share to Gene Expression Regulation

Share to Germ-Line Mutation

Share to RNA, Messenger

Source

Open in PubMed Open full text

Identifiers

PMID: 26511139
DOI: 10.1186/s13046-015-0244-4
PMCID: PMC4625907

Genes

APC
MUTYH
FAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Correlation between mutations and mRNA expression of APC and MUTYH genes: new insight into hereditary colorectal polyposis predisposition.PMID 26511139Read ↗

APC and MUTYH Analysis in FAP Patients: A Novel Mutation in APC Gene and Genotype-Phenotype CorrelationSemantic proximity Read ↗

Contribution of APC and MUTYH mutations to familial adenomatous polyposis susceptibility in Hungary.Semantic proximity Read ↗

Mutational spectrum of the APC and MUTYH genes and genotype-phenotype correlations in Brazilian FAP, AFAP, and MAP patients.Semantic proximity Read ↗

The genetics of familial adenomatous polyposis (FAP) and MutYH-associated polyposis (MAP).Semantic proximity Read ↗

Clinical and molecular features of attenuated adenomatous polyposis in northern Italy.Semantic proximity Read ↗

Molecular analysis of the APC and MUTYH genes in Galician and Catalonian FAP families: a different spectrum of mutations?Semantic proximity Read ↗

MUTYH-associated polyposis (MAP).Semantic proximity Read ↗

Relative role of APC and MUTYH mutations in the pathogenesis of familial adenomatous polyposis.Semantic proximity Read ↗

Heterogeneous molecular mechanisms underlie attenuated familial adenomatous polyposis.Semantic proximity Read ↗

MUTYH-associated polyposis - variability of the clinical phenotype in patients with biallelic and monoallelic MUTYH mutations and report on novel mutations.Semantic proximity Read ↗

Adenomatous Polyposis Families That Screen APC Mutation–Negative by Conventional Methods Are Genetically HeterogeneousSemantic proximity Read ↗

MUTYH Associated Polyposis (MAP)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.