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Article

BDNF Val66Met polymorphism is associated with aggressive behavior in schizophrenia.

European psychiatry : the journal of the Association of European Psychiatrists - 1 Oct 2010

Spalletta G, Morris D W, Angelucci F, Rubino I A, Spoletini I, Bria P, Martinotti G, Siracusano A, Bonaviri G, Bernardini S, Caltagirone C, Bossù P, Donohoe G, Gill M, Corvin A P

Abstract excerpt

Brain-derived neurotrophic factor (BDNF) gene variants may potentially influence behaviour. In order to test this hypothesis, we investigated the relationship between BDNF Val66Met polymorphism and aggressive behaviour in a population of schizophrenic patients. Our results showed that increased number of BDNF Met alleles was associated with increased aggressive behaviour.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20430595
DOI: 10.1016/j.eurpsy.2009.10.008

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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