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Article

Additive effects of LPL, APOA5 and APOE variant combinations on triglyceride levels and hypertriglyceridemia: results of the ICARIA genetic sub-study.

BMC medical genetics - 29 Apr 2010

Ariza María-José, Sánchez-Chaparro Miguel-Angel, Barón Francisco-Javier, Hornos Ana-María, Calvo-Bonacho Eva, Rioja José, Valdivielso Pedro, Gelpi José-Antonio, González-Santos Pedro

Abstract excerpt

BACKGROUND: Hypertriglyceridemia (HTG) is a well-established independent risk factor for cardiovascular disease and the influence of several genetic variants in genes related with triglyceride (TG) metabolism has been described, including LPL, APOA5 and APOE. The combined analysis of these polymorphisms could produce clinically meaningful complementary information. METHODS: A subgroup of the ICARIA study...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20429872
DOI: 10.1186/1471-2350-11-66
PMCID: PMC2877669

Genes

APOE
LPL
APOA5

Variants

rs320
rs320
rs320
rs320

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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