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Article

Frequency of rare mutations and common genetic variations in severe hypertriglyceridemia in the general population of Spain.

Lipids in health and disease - 23 Apr 2016

Lamiquiz-Moneo Itziar, Blanco-Torrecilla Cristian, Bea Ana M, Mateo-Gallego Rocío, Pérez-Calahorra Sofía, Baila-Rueda Lucía, Cenarro Ana, Civeira Fernando, de Castro-Orós Isabel

Abstract excerpt

BACKGROUND: Hypertriglyceridemia (HTG) is a common complex metabolic trait that results of the accumulation of relatively common genetic variants in combination with other modifier genes and environmental factors resulting in increased plasma triglyceride (TG) levels. The majority of severe primary hypertriglyceridemias is diagnosed in adulthood and their molecular bases have not been fully defined yet. The...

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Source

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Identifiers

PMID: 27108409
DOI: 10.1186/s12944-016-0251-2
PMCID: PMC4842266

Genes

APOA5
APOE
GPIHBP1
LMF1
LPL
APOC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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