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Article

Polymorphisms in APOA1 and LPL genes are statistically independently associated with fasting TG in men with CAD.

European journal of human genetics : EJHG - 1 Apr 2005

Souverein Olga W, Jukema J Wouter, Boekholdt S Matthijs, Zwinderman Aeilko H, Tanck Michael W T

Abstract excerpt

The objective of this paper was to identify the single nucleotide polymorphisms (SNPs) that show unshared effects on plasma triglyceride (TG) levels and to investigate whether these SNPs show statistically independent effects on plasma TG levels. In total, 59 polymorphisms in 20 genes involved in lipid metabolism were investigated. Polymorphisms were selected for a multivariate ANOVA model if they showed an...

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Source

Identifiers

PMID: 15657615
DOI: 10.1038/sj.ejhg.5201362

Genes

LPL
APOA1
ABCA1
APOC3
APOE
CAD
LIPC

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

Polymorphisms in APOA1 and LPL genes are statistically independently associated with fasting TG in men with CAD.PMID 15657615Read ↗

Additive effects of LPL, APOA5 and APOE variant combinations on triglyceride levels and hypertriglyceridemia: results of the ICARIA genetic sub-study.Semantic proximity Read ↗

Genetic association of LPL rs1121923 and rs258 with plasma TG and VLDL levelsSemantic proximity Read ↗

The postprandial chylomicron triacylglycerol response to dietary fat in healthy male adults is significantly explained by a combination of single nucleotide polymorphisms in genes involved in triacylglycerol metabolism.Semantic proximity Read ↗

SNPs at the APOA5 gene account for the strong association with hypertriglyceridaemia at the APOA5/A4/C3/A1 locus on chromosome 11q23 in the Northern Irish population.Semantic proximity Read ↗

Contribution of APOA5 gene variants to plasma triglyceride determination and to the response to both fat and glucose tolerance challenges.Semantic proximity Read ↗

A single nucleotide polymorphism in APOA5 determines triglyceride levels in Hong Kong and Guangzhou Chinese.Semantic proximity Read ↗

Polymorphism in the promoter region of the apolipoprotein A5 gene is associated with an increased susceptibility for coronary artery disease.Semantic proximity Read ↗

Novel polymorphisms in promoter region of atp binding cassette transporter gene and plasma lipids, severity, progression, and regression of coronary atherosclerosis and response to therapy.Semantic proximity Read ↗

Genetic variant R952Q in LRP8 is associated with increased plasma triglyceride levels in patients with early-onset CAD and MI.Semantic proximity Read ↗

APOA5 polymorphisms influence plasma triglycerides in young, healthy African Americans and whites of the CARDIA Study.Semantic proximity Read ↗

Gender- and obesity-specific effect of apolipoprotein C3 gene (APOC3) -482C>T polymorphism on triglyceride concentration in Turkish adults.Semantic proximity Read ↗

Interactions of the LIPG 584C>T polymorphism and alcohol consumption on serum lipid levels.Semantic proximity Read ↗

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