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Adolescent idiopathic scoliosis and genetic testing.

Current opinion in pediatrics - 1 Feb 2010

Ogilvie James

Abstract excerpt

PURPOSE OF REVIEW: Adolescent idiopathic scoliosis (AIS) is the most common spinal deformity affecting 2% of the population. Initial diagnosis is straightforward. Determining which curves will progress and warrant intervention is still problematic. Recent genetics research has discovered markers that are associated with progression to a severe curve, providing new information that can lead to more effective care...

Topics

Adolescent
Disease Progression
Genetic Markers
Genetic Testing
Genome-Wide Association Study
Humans
Mass Screening
Polymorphism, Single Nucleotide
School Health Services
Scoliosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 19949338
DOI: 10.1097/MOP.0b013e32833419ac

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