Article
Recent progress in AML with recurrent genetic abnormalities.
International journal of hematology - 1 Nov 2024
Ishikawa Yuichi
Abstract excerpt
Acute myeloid leukemia (AML) is a heterogeneous disease characterized by various molecular abnormalities that significantly impact its pathogenesis and prognosis. Currently, the prognosis of AML patients is stratified on the basis of co-existing chromosomal and genetic abnormalities. AML patients with NPM1 or CEBPA mutations, which are frequently identified in cytogenetically normal AML, are classified in the...
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