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Article

Interleukin-18 gene polymorphisms and rheumatoid arthritis: a meta-analysis.

Gene - 1 Jul 2013

Ji Jong Dae, Lee Won Jin

Abstract excerpt

Interleukin-18 (IL-18) is a member of the IL-1 superfamily that enhances both innate and acquired immune responses. IL-18 is highly expressed in sera, synovial fluids and synovial tissues of patients with RA, and these IL-18 levels are correlated with RA disease activity, indicating an important role of IL-18 in the pathogenesis of RA. Several studies have examined the association of IL-18 gene polymorphisms with...

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PMID: 23587914
DOI: 10.1016/j.gene.2013.03.132

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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