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Parkin mutations and phenotypic features in Czech patients with early-onset Parkinson's disease.

Neuro endocrinology letters - 1 Jan 2010

Fiala Ondrej, Pospisilova Lenka, Prochazkova Jana, Matejckova Milada, Martasek Pavel, Novakova Lucie, Roth Jan, Ruzicka Evzen

Abstract excerpt

OBJECTIVES: Mutations in several genes such as parkin can be detected in up to 20% of patients with early-onset Parkinson's disease (EOPD). The aim of our study was to determine the frequency of parkin alterations and phenotypic characteristics in Czech EOPD patients. METHODS: A total of 45 EOPD individuals (age at onset <45 years) were phenotyped and screened for parkin mutations. RESULTS: In total, 19 patients...

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PMID: 20424582

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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