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Low frequency of the PARK2 gene mutations in Polish patients with the early-onset form of Parkinson disease.

Parkinsonism & related disorders - 1 Feb 2010

Koziorowski Dariusz, Hoffman-Zacharska Dorota, Sławek Jarosław, Szirkowiec Walentyna, Janik Piotr, Bal Jerzy, Friedman Andrzej

Abstract excerpt

OBJECTIVE: Mutations in the PARK2 (Parkin) gene result in an early-onset autosomal recessive form of Parkinson Disease (EO-PD). Although the frequency of the PARK2 mutations in EO-PD patients according to several studies is high and has been reported in up to 50% in familial and 19% in sporadic cases, these data remain controversial. METHODS: We performed PARK2 gene analysis for a group of 79 Polish EO-PD...

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Identifiers

PMID: 19628420
DOI: 10.1016/j.parkreldis.2009.06.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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