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Article

A conserved methionine residue controls the substrate selectivity of a neuronal glutamate transporter.

The Journal of biological chemistry - 9 Jul 2010

Rosental Noa, Kanner Baruch I

Abstract excerpt

Glutamate transporters located in the brain maintain low synaptic concentrations of the neurotransmitter by coupling its flux to that of sodium and other cations. In the binding pocket of the archeal homologue Glt(Ph), a conserved methionine residue has been implicated in the binding of the benzyl moiety of the nontransportable substrate analogue threo-beta-benzyloxyaspartate. To determine whether the...

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Identifiers

PMID: 20424168
DOI: 10.1074/jbc.M109.087163
PMCID: PMC2898430

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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