Article
Identification of malignant cell clones in radio-induced murine thymic lymphomas by viral and cellular probes.
Leukemia - 1 Apr 1990
Astier-Gin T, Legrand E, Baylac-Kalabokias H, Guillemain B
Abstract excerpt
The role of B ecotropic recombinant retroviruses in the emergence and the progression of radio-induced thymic lymphomas was evaluated by analyzing the cell populations present in nine primary and in in vivo propagated tumors. For this, tumor DNAs were analyzed by the Southern method using probes...
Topics
- Animals
- Clone Cells
- DNA Probes
- DNA, Neoplasm
- DNA, Viral
- Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
- Immunoglobulin Heavy Chains
- Lymphoma
- Mice
- Mice, Inbred Strains
- Neoplasm Transplantation
- Neoplasms, Radiation-Induced
- Phenotype
- Receptors, Antigen, T-Cell
- T-Lymphocytes
- Thymus Neoplasms
