Article
Oligoclonality of Moloney leukemias.
Leukemia research - 1 Aug 1992
Ofir R, Gopas J, Aflalo E, Weinstein Y
Abstract excerpt
Induction of leukemia by non-transforming retroviruses results in the appearance of various hematopoietic tumors. It is believed that these tumors are monoclonal. In this work, the clonal nature of Moloney leukemia virus (MoLV)-induced tumors was studied. Two genetic parameters were used in order to identify leukemic clones: the pattern of the proviral integration sites and the rearrangement of the T-cell...
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