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Article

Parkinson's disease: insights from pathways.

Human molecular genetics - 15 Apr 2010

Cookson Mark R, Bandmann Oliver

Abstract excerpt

Parkinson's disease (PD) typically presents in sporadic fashion, but the identification of disease-causing mutations in monogenically inherited PD genes has provided crucial insight into the pathogenesis of this disorder. Mutations in autosomal recessively inherited genes, namely parkin, PINK1 and DJ-1, typically lead to early onset parkinsonism. At least two of these genes (PINK1 and parkin) appear to work in...

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Source

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Identifiers

PMID: 20421364
DOI: 10.1093/hmg/ddq167
PMCID: PMC2875048

Genes

PINK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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