Article
Understanding the molecular causes of Parkinson's disease.
Trends in molecular medicine - 1 Nov 2006
Wood-Kaczmar A, Gandhi S, Wood N W
Abstract excerpt
Parkinson's disease (PD) is a neurodegenerative disease that is both common and incurable. The majority of cases are sporadic and of unknown origin but several genes have been identified that, when mutated, give rise to rare, familial forms of the disease. The principal genes that have been shown to cause PD are alpha-synuclein (SNCA), parkin, leucine-rich repeat kinase 2 (LRRK2), PTEN-induced putative kinase 1...
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