Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional role of charged residues in drosomycin, a Drosophila antifungal peptide.

Developmental and comparative immunology - 1 Sept 2010

Zhang Zhenting, Zhu Shunyi

Abstract excerpt

The functional importance of positively charged residues in antibacterial peptides (ABPs) has been well documented. However, their role in antifungal peptides (AFPs) has not been extensively evaluated. To address this question, we investigated the functional role of charged residues in drosomycin, a specific Drosophila antifungal peptide, using site-directed mutagenesis in combination with circular dichroism (CD)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal Agents
Share to Circular Dichroism
Share to Drosophila

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Growth Inhibitors

Share to Immunity

Share to Mycoses

Share to Peptide Fragments

Source

Identifiers

PMID: 20420852
DOI: 10.1016/j.dci.2010.04.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional role of charged residues in drosomycin, a Drosophila antifungal peptide.PMID 20420852Read ↗

Gene expression divergence and evolutionary analysis of the drosomycin gene family in Drosophila melanogaster.Semantic proximity Read ↗

De-novo design of antimicrobial peptides for plant protection.Semantic proximity Read ↗

Optimization of the antifungal properties of the bacterial peptide EntV by variant analysisSemantic proximity Read ↗

Global phenotype screening and transcript analysis outlines the inhibitory mode(s) of action of two amphibian-derived, alpha-helical, cationic peptides on Saccharomyces cerevisiae.Semantic proximity Read ↗

Role of unique basic residues in cytotoxic, antibacterial and antiparasitic activities of human eosinophil cationic protein.Semantic proximity Read ↗

The Drosophila Toll-9 activates a constitutive antimicrobial defense.Semantic proximity Read ↗

Naturally processed dermcidin-derived peptides do not permeabilize bacterial membranes and kill microorganisms irrespective of their charge.Semantic proximity Read ↗

Molecular dynamics studies of the antimicrobial peptides piscidin 1 and its mutants with a DOPC lipid bilayer.Semantic proximity Read ↗

Functional characterization of naturally occurring melittin peptide isoforms in two honey bee species, Apis mellifera and Apis cerana.Semantic proximity Read ↗

Role of arginine and lysine in the antimicrobial mechanism of histone-derived antimicrobial peptides.Semantic proximity Read ↗

Structural characterization and functional analysis of juvenile hormone diol kinase from the silkworm, Bombyx mori.Semantic proximity Read ↗

Reduction of drosopterin content caused by a 45-nt insertion in Henna pre-mRNA of Drosophila melanogaster.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.