Article
Structural characterization and functional analysis of juvenile hormone diol kinase from the silkworm, Bombyx mori.
International journal of biological macromolecules - 15 Jan 2021
Xu Haiyang, Zhang Yunshi, Zhang Li, Wang Zhan, Guo Pengchao, Zhao Ping
Abstract excerpt
Juvenile hormone diol kinase (JHDK) is an important enzyme involved in the juvenile hormone metabolism pathway, which catalyzes the phosphorylation of juvenile hormone diol to form the polar metabolite JH diol phosphate. Here, we reported the first crystal structure of insect JHDK from Bombyx mori, BmJHDK-L2, determined at a resolution of 1.22 Å. The structure of BmJHDK-L2 mainly comprises of eight α-helical...
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