Article
Reduction of drosopterin content caused by a 45-nt insertion in Henna pre-mRNA of Drosophila melanogaster.
Science in China. Series C, Life sciences - 1 Aug 2008
Wang Qin, Zhao Chunjiang, Bai Lihua, Deng Xuemei, Wu Changxin
Abstract excerpt
Phenylalanine hydroxylase is assumed to be a key enzyme in drosopterin metabolism, but direct in vivo evidence to support this hypothesis is still absent. In the present study, we found a new natural recessive purple eye mutant of Drosophila melanogaster, Hn ( bp ), which was a 45-nt insertion mutant in the second exon of Henna. The insertion resulted in a predicted protein with 15 additional amino acids as...
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