Article
De-novo design of antimicrobial peptides for plant protection.
PloS one - 1 Jan 2013
Zeitler Benjamin, Herrera Diaz Areli, Dangel Alexandra, Thellmann Martha, Meyer Helge, Sattler Michael, Lindermayr Christian
Abstract excerpt
This work describes the de-novo design of peptides that inhibit a broad range of plant pathogens. Four structurally different groups of peptides were developed that differ in size and position of their charged and hydrophobic clusters and were assayed for their ability to inhibit bacterial growth and fungal spore germination. Several peptides are highly active at concentrations between 0,1 and 1 µg/ml against...
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