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Article

Diversity of preferred nucleotide sequences around the translation initiation codon in eukaryote genomes.

Nucleic acids research - 1 Feb 2008

Nakagawa So, Niimura Yoshihito, Gojobori Takashi, Tanaka Hiroshi, Miura Kin-ichiro

Abstract excerpt

Understanding regulatory mechanisms of protein synthesis in eukaryotes is essential for the accurate annotation of genome sequences. Kozak reported that the nucleotide sequence GCCGCC(A/G)CCAUGG (AUG is the initiation codon) was frequently observed in vertebrate genes and that this 'consensus' sequence enhanced translation initiation. However, later studies using invertebrate, fungal and plant genes reported...

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Identifiers

PMID: 18086709
DOI: 10.1093/nar/gkm1102
PMCID: PMC2241899

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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