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Article

Axonal degeneration in the Trembler-j mouse demonstrated by stimulated single-fiber electromyography.

Muscle & nerve - 1 Jul 2007

Meekins Gregg D, Carter Gregory T, Emery Michael J, Weiss Michael D

Abstract excerpt

The Trembler-j (Tr-j) mouse is a naturally occurring mutant with a point mutation in the peripheral myelin protein-22 gene causing severe peripheral nerve demyelination. It is a genetically homologous murine model for Charcot-Marie-Tooth disease type 1A (CMT 1A). Our prior pilot studies using stimulated single-fiber needle electromyograpy (SSFEMG) showed increased jitter in 60-day-old Tr-j mice compared to...

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PMID: 17443662
DOI: 10.1002/mus.20786

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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