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Article

Early Changes in Skeletal Muscle of Young C22 Mice, A Model of Charcot-Marie-Tooth 1A.

Journal of neuromuscular diseases - 1 Jan 2021

Deres Friederike, Schwartz Stephanie, Kappes-Horn Karin, Kornblum Cornelia, Reimann Jens

Abstract excerpt

BACKGROUND: The C22 mouse is a Charcot-Marie-Tooth 1A transgenic model with minimal axonal loss. OBJECTIVE: To analyse early skeletal muscle changes resulting from this dysmyelinating neuropathy. METHODS: Histology of tibialis anterior muscles of C22 mice and wild type litter mate controls for morphometric analysis and (immuno-)histochemistry for known denervation markers and candidate proteins identified by...

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Identifiers

PMID: 34459411
DOI: 10.3233/JND-210681
PMCID: PMC8673495

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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